ligand

2024-04-30


Mathematically modelling metal-ligand bonding in late transition-metal complexes has been an important tool in catalyst development — although lacking for early transition metals such as Cr ...

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. The etymology stems from Latin ligare, which means 'to bind'. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein.

Ligands are ions or neutral molecules that bond to a central metal atom or ion. Ligands act as Lewis bases (electron pair donors), and the central atom acts as a Lewis acid (electron pair acceptor). Ligands have at least one donor atom with an electron pair used to form covalent bonds with the central atom.

LIGAND is a composite database comprising three sections: COMPOUND for the information about metabolites and other chemical compounds, REACTION for the collection of substrate-product relations representing metabolic and other reactions, and ENZYME for the information about enzyme molecules.

A ligand is a molecule or ion that can donate a pair of electrons to a central metal atom or ion. The web page explains the types of ligands (monodentate, bidentate, polydentate, and ambidentate) based on the number of binding sites with the metal, charge, and size. It also discusses the chelating effect of ligands and their applications in chemistry.

Learn about different types of signaling molecules and the receptors they bind to on target cells. Explore intracellular receptors, ligand-gated ion channels, G protein-coupled receptors, and receptor tyrosine kinases.

The ligand is a chemical messenger released by one cell to signal either itself or a different cell. The binding results in a cellular effect, which manifests as any number of changes in that cell, including altering gene transcription or translation or changing cell morphology.

5.2: Ligands and Nomenclature. Rule 1: If ions are present, name the cation first, followed by the anion. Rule 3: Specify the identity, number, and as appropriate, isomerism of the ligands present in alphabetical order by ligand name. Rule 5: Specify the valence of the metal.

A ligand is a complexing group that donates or shares electrons with a central atom or ion. Learn about the types, examples, and sources of ligands in chemistry, such as water, ammonia, and 1,4,7-triazaheptane.

In general, receptors are very speci c for their ligands, but the specificity is not mutual: ligands can be rather promiscuous and bind with multiple receptors. This is part of the coordination aspect of signaling, though as a single ligand can initiate different effects in different cells depending on what receptor is expressed.

Peta Situs